Citations
More than 900 publications citing the Sentieon Software from multiple study areas
Genetic Disease
Clinical whole genome, exome, and panel sequencing. Selected Citation List
Tumor Sequencing
Accurately identify variants from fresh, frozen, and FFPE biopsies or blood samples. Selected Citation List
Agrigenomics
Analyze complex and polyploid plant and animal genomes. Selected Citation List
Population Sequencing
Cost-effective whole genome and exome sequencing joint genotyping of large cohorts. Selected Citation List
Multi-omics
Analyze genomic variants, gene expression, methylation and other datasets simultaneously. Selected Citation List
Gene Editing
Screen whole genome for off-target events and calculate editing efficiency. Selected Citation List
Sentieon Preprints
To Cite Sentieon® tools, please consider the corresponding pipeline publications listed below.
- [non-UMI ctDNA - BioRxiv 2024] - Optimizing Accuracy and Efficiency in Analyzing Non-UMI Liquid Biopsy Datasets Using the Sentieon ctDNA Pipeline
- [Gene Editing - JGG 2023] - CRISPR-detector: fast and accurate detection, visualization, and annotation of genome-wide mutations induced by genome editing events
- [DNAscope - BioRxiv 2022] - DNAscope: High accuracy small variant calling using machine learning
- [DNAscope LongRead - BioRxiv 2022] - Sentieon DNAscope LongRead – A highly Accurate, Fast, and Efficient Pipeline for Germline Variant Calling from PacBio HiFi reads
- [UMI - BioRxiv 2022] - Processing UMI Datasets at High Accuracy and Efficiency with the Sentieon ctDNA Analysis Pipeline
- [TNscope - BioRxiv 2018] - TNscope: Accurate Detection of Somatic Mutations with Haplotype-based Variant Candidate Detection and Machine Learning Filtering
- [DNAseq/TNseq - BioRxiv 2017] - The Sentieon Genomics Tools - A fast and accurate solution to variant calling from next-generation sequence data
- [DNAseq - PeerJ 2016] - Sentieon DNA Pipeline for Variant Detection, Software-only solution, over 20X faster than GATK 3.3 with identical results
Selected Third Party Benchmark Publications:
- [DNAscope - BioRxiv 2022] - Sequencing by avidity enables high accuracy with low reagent consumption
- [DNAscope - BMC Genomics 2022] - Accuracy benchmark of the GeneMind GenoLab M sequencing platform for WGS and WES analysis
- [TNscope - Briefings in Bioinformatics 2020] - Benchmarking variant callers in next-generation and third-generation sequencing analysis
- [DNAscope - BioRxiv 2020] - Advanced Whole Genome Sequencing Using an Entirely PCR-free Massively Parallel Sequencing Workflow
- [DNAseq - Frontiers 2019] - Sentieon DNASeq Variant Calling Workflow Demonstrates Strong Computational Performance and Accuracy
Blogs and Use Cases
Selected blogs and use cases from industry collaborators
- Intel Health Analytics Solution Brief - Streamlining Genomic Analysis with Faster and More Accurate Technology
- Intel Developers Blog - Delivering Cost-Effective Genomics for Precision Medicine; Comparing Sentieon DNASeq Performance to NVIDIA Clara Parabricks
- Intel Health Analytics Solution Brief - Intel CPUs deliver breakthrough speed for genomic analysis
- Amazon Omics Blog - Amazon Omics now supports Sentieon genomic analysis pipelines
- Microsoft Healthcare and Life Sciences Blog - Sentieon pipelines on Azure – An overview
- Oracle Cloud Infrastructure Blog - Oracle Cloud and Sentieon DNAseq enable processing of 30X WGS samples from FASTQ to VCF in about an hour and less than $1 in on-demand costs
- ByteDance Volcengine Blog - (written in Chinese) Volcano Engine Bio-OS Platform empowers Sentieon to achieve efficient and precise genomic analysis
- Golden Helix Blog - Sentieon’s Latest Enhancements Powering VarSeq 2.5.0: Accelerating Clinical Workflows and Data Analysis in NGS
- Golden Helix Blog - Top 5 Features of Sentieon
- Golden Helix Blog - Sentieon Updates: Now Supporting Long-Read Alignment and Calling
- DNAnexus Science Frontiers - An exploration of machine-learning based variant callers for SNV and small-indel using PacBio HiFi data
- DNANexus Case Study - Calling Somatic Variants with Sentieon on DNANexus
- DNANexus Case Study - Trio Analysis with Sentieon Rapid DNASeq on DNAnexus
- Memory Machine Cloud Blog - Sentieon Genomics Tools: Boosting Performance with Memory Machine Cloud (complete report)